Nov 3rd 2025
Vitamin D2 versus Vitamin D3
. . . What's the difference? If you get the 25(OH)D test for vitamin D status that we urge everyone to get, you’re likely to find you’re deficient. It’s also likely your doctor will offer you a prescription for Drisdol, a synthetic form of vitamin D. Thank your doctor, but call us rather than fill that prescription. Drisdol is vitamin D2, a form of vitamin D that is less effective than vitamin D3 (the form of vitamin D we carry) and may even be harmful. There are two basic forms of vitamin D – vitamin D2 and vitamin D3. D3 (cholecalciferol) is the preferred form. It’s what’s made in our skin from sunlight; it’s also found in eggs, organ meats, animal fat and fish oil. Vitamin D2 (ergocalciferol) is synthesized by irradiating yeast or fungi. It isn’t generally found in the human body. Because it’s easier and less expensive to manufacture, D2 is the form most often used for food fortification and in medications. But it’s more difficult for the body to utilize and may even be detrim…
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